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M.D.L. O’Connell, A. Tajar, T.W. O’Neill, S.A. Roberts, D.M. Lee, S.R. Pye, A.J Silman, J.D. Finn, G. Bartfai, S. Boonen, F.F. Casanueva, G. Forti, A. Giwercman, T.S. Han, I.T. Huhtaniemi, K. Kula, M.E.J. Lean, N. Pendleton, M. Punab, D. Vanderschueren, F.C.W. Wu

J Frailty Aging 2013;2(2):77-83

Objectives: Adapt a measure of frailty for use in a cohort study of European men and explore relationships with age, health related quality of life and falls. Design: Longitudinal cohort study. Setting: 8 European centers. Participants: 3047 men aged 40-79 participating in the European Male Ageing Study (EMAS). Measurements: Frailty was assessed using an adaptation of the Cardiovascular Health Study criteria. Health related quality of life was evaluated using the Rand Short Form-36 (SF-36) questionnaire which comprises both mental and physical component scores. Self reported falls in the preceding 12 months were recorded at 2-year follow-up. Results: 78 men (2.6%) were classified as frail (≥3 criteria) and 821 (26.9%) as prefrail (1-2 criteria). The prevalence of frailty increased from 0.1% in men aged 40-49 up to 6.8% in men aged 70-79. Compared to robust men, both prefrail and frail men had lower health related quality of life. Frailty was more strongly associated with the physical than mental subscales of the SF-36. Frailty was associated with higher risk of falls OR (95% CI) 2.92 (1.52, 5.59). Conclusions: Frailty, assessed by the EMAS criteria, increased in prevalence with age and was related to poorer health related quality of life and higher risk of falls in middle-aged and older European men. These criteria may help to identify a vulnerable subset of older men.

M.D.L. O’Connell ; A. Tajar ; T.W. O’Neill ; S.A. Roberts ; D.M. Lee ; S.R. Pye ; A.J. Silman ; J.D. Finn ; G. Bartfai ; S. Boonen ; F.F. Casanueva ; G. Forti ; A. Giwercman ; T.S. Han ; I.T. Huhtaniemi ; K. Kula ; M.E.J. Lean ; N. Pendleton ; M. Punab ; D. Vanderschueren ; F.C.W. Wu ; and the EMAS group ; (2013): FRAILTY IS ASSOCIATED WITH IMPAIRED QUALITY OF LIFE AND FALLS IN MIDDLE-AGED AND OLDER EUROPEAN MEN . The Journal of Frailty and Aging (JFA). http://dx.doi.org/10.14283/jfa.2013.12

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